Webinar replay: Compassionate Overdose Response Summit and Naloxone Dosing Meeting
The Compassionate Overdose Response Summit and Naloxone Dosing Meeting, held on March 18-19, 2024, was a two-day summit where naloxone experts built consensus on the definition of a compassionate bystander overdose response.
Day 1 (March 18) was an invitation-only for a small group of researchers, people with lived experience of overdose, those who have reversed multiple overdoses, and medical providers tasked with drafting an issue brief that will be the basis for the remainder of the summit.
Day 2 (March 19) was an open virtual summit. On this day, we shared the issue brief with the audience for feedback and host multiple presentations that covered emerging research on this topic, including:
- The impact of different naloxone doses and formulations on people who receive them
- The role of oxygen in community overdose response
- Communication strategies for bystander overdose response steps
The event produced clear guidance on naloxone dosing and the role of oxygen in overdose response:
- There is no real-world evidence for high-dose or long-acting opioid antagonists; therefore, until there is community experience with those regimens, they should not be included in standing orders or made available for broad community use.
- Rescue breathing is standard overdose response protocol and should be included in educational materials and training.
- People who use drugs must be central to the design, development, purchasing and distribution of all overdose reversal products
Additional materials from this event are below:
- Compassionate Overdose Response Summit Agenda
- Missouri’s Overdose Field Report: Naloxone dosing remains stable despite concerns otherwise
- Understanding negative reactions following overdose reversal with naloxone
- Examination of Naloxone Dosing Patterns for Opioid Overdose by Emergency Medical Services in Kentucky during Increased Fentanyl Use from 2018 to 2021
- Two decades of data: Insights from syringe service participants and EMS
- Scope of international research and what are the next research questions
For justification for the above statements or for questions, please contact Erin Russell.
